Gas-Phase Collisions with Trimethylamine-N-Oxide Enable Activation-Controlled Protein Ion Charge Reduction

Modulating protein ion charge is a useful tool for the study of protein folding and interactions by electrospray ionization mass spectrometry. Here, we investigate activation-dependent charge reduction of protein ions with the chemical chaperone trimethylamine-N-oxide (TMAO). Based on experiments ca...

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Detalles Bibliográficos
Autores principales: Kaldmäe, Margit, Österlund, Nicklas, Lianoudaki, Danai, Sahin, Cagla, Bergman, Peter, Nyman, Tomas, Kronqvist, Nina, Ilag, Leopold L., Allison, Timothy M., Marklund, Erik G., Landreh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Focus: Emerging Investigators: Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669196/
https://www.ncbi.nlm.nih.gov/pubmed/31286443
http://dx.doi.org/10.1007/s13361-019-02177-8

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