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NOX2 mediates quiescent handling of dead cell remnants in phagocytes

The phagocyte NADPH oxidase (the NOX2 complex) generates superoxide, the precursor to reactive oxygen species (ROS). ROS possess both antimicrobial and immunoregulatory function. Inactivating mutations in alleles of the NOX2 complex cause chronic granulomatous disease (CGD), characterized by an enha...

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Detalles Bibliográficos
Autores principales:	Hahn, Jonas, Euler, Maximilien, Kilgus, Emelie, Kienhöfer, Deborah, Stoof, Julia, Knopf, Jasmin, Hahn, Madelaine, Harrer, Thomas, Hultqvist, Malin, Olofsson, Peter, Mokhir, Andriy, Holmdahl, Rikard, Herrmann, Martin, Schett, Georg, Muñoz, Luis E., Hoffmann, Markus H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669319/ https://www.ncbi.nlm.nih.gov/pubmed/31349119 http://dx.doi.org/10.1016/j.redox.2019.101279

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