Cargando…
GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition
Transition of acute kidney injury (AKI) to chronic kidney disease (CKD) represents an important cause of kidney failure. However, how AKI is transformed into CKD remains elusive. Following folic acid injury, mice developed AKI with ensuing CKD transition, featured by variable degrees of interstitial...
Autores principales: | Lu, Minglei, Wang, Pei, Qiao, Yingjin, Jiang, Chunming, Ge, Yan, Flickinger, Bryce, Malhotra, Deepak K., Dworkin, Lance D., Liu, Zhangsuo, Gong, Rujun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669347/ https://www.ncbi.nlm.nih.gov/pubmed/31349118 http://dx.doi.org/10.1016/j.redox.2019.101275 |
Ejemplares similares
-
Activation of mineralocorticoid receptor by ecdysone, an adaptogenic and anabolic ecdysteroid, promotes glomerular injury and proteinuria involving overactive GSK3β pathway signaling
por: Lu, Minglei, et al.
Publicado: (2018) -
Permissive effect of GSK3β on profibrogenic plasticity of renal tubular cells in progressive chronic kidney disease
por: Chen, Bohan, et al.
Publicado: (2021) -
The ageing kidney: Molecular mechanisms and clinical
implications
por: Fang, Yudong, et al.
Publicado: (2020) -
Age-related GSK3β overexpression drives podocyte senescence and glomerular aging
por: Fang, Yudong, et al.
Publicado: (2022) -
Therapeutic Targeting of SGLT2: A New Era in the Treatment of Diabetes and Diabetic Kidney Disease
por: Shaffner, James, et al.
Publicado: (2021)