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Vaccine Evolution and Its Application to Fight Modern Threats

Before the development of the first vaccine, infectious diseases were a major cause of death around the globe with life expectancy estimated to be <50 years. Three measures have helped to drastically reduce the burden of infectious diseases but only vaccines have proven to be able to eradicate in...

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Detalles Bibliográficos
Autores principales: Andreano, Emanuele, D'Oro, Ugo, Rappuoli, Rino, Finco, Oretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669413/
https://www.ncbi.nlm.nih.gov/pubmed/31404139
http://dx.doi.org/10.3389/fimmu.2019.01722
Descripción
Sumario:Before the development of the first vaccine, infectious diseases were a major cause of death around the globe with life expectancy estimated to be <50 years. Three measures have helped to drastically reduce the burden of infectious diseases but only vaccines have proven to be able to eradicate infectious agents. Herein, we describe new methodologies that have paved the way for what is currently known as modern vaccinology and the use of vaccines to tackle antimicrobial resistance, the biggest global threat of our time.