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Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

Noroviruses, in the genus Norovirus, are a significant cause of viral gastroenteritis in humans and animals. For almost 50 years, the lack of a cultivation system for human noroviruses (HuNoVs) was a major barrier to understanding virus biology and the development of effective antiviral strategies....

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Detalles Bibliográficos
Autores principales: Estes, Mary K., Ettayebi, Khalil, Tenge, Victoria R., Murakami, Kosuke, Karandikar, Umesh, Lin, Shih-Ching, Ayyar, B. Vijayalakshmi, Cortes-Penfield, Nicolas W., Haga, Kei, Neill, Frederick H., Opekun, Antone R., Broughman, James R., Zeng, Xi-Lei, Blutt, Sarah E., Crawford, Sue E., Ramani, Sasirekha, Graham, David Y., Atmar, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669637/
https://www.ncbi.nlm.nih.gov/pubmed/31336765
http://dx.doi.org/10.3390/v11070638