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Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata)

Warmer seawater temperatures are expected to increase harmful algal blooms (HABs) occurrence, intensity, and distribution. Yet, the potential interactions between abiotic stressors and HABs are still poorly understood from ecological and seafood safety perspectives. The present study aimed to invest...

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Autores principales: Barbosa, Vera, Santos, Marta, Anacleto, Patrícia, Maulvault, Ana Luísa, Pousão-Ferreira, Pedro, Costa, Pedro Reis, Marques, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669718/
https://www.ncbi.nlm.nih.gov/pubmed/31337041
http://dx.doi.org/10.3390/toxins11070408
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author Barbosa, Vera
Santos, Marta
Anacleto, Patrícia
Maulvault, Ana Luísa
Pousão-Ferreira, Pedro
Costa, Pedro Reis
Marques, António
author_facet Barbosa, Vera
Santos, Marta
Anacleto, Patrícia
Maulvault, Ana Luísa
Pousão-Ferreira, Pedro
Costa, Pedro Reis
Marques, António
author_sort Barbosa, Vera
collection PubMed
description Warmer seawater temperatures are expected to increase harmful algal blooms (HABs) occurrence, intensity, and distribution. Yet, the potential interactions between abiotic stressors and HABs are still poorly understood from ecological and seafood safety perspectives. The present study aimed to investigate, for the first time, the bioaccumulation/depuration mechanisms and ecotoxicological responses of juvenile gilthead seabream (Sparus aurata) exposed to paralytic shellfish toxins (PST) under different temperatures (18, 21, 24 °C). PST were detected in fish at the peak of the exposure period (day five, 0.22 µg g(−1) N-sulfocarbamoylGonyautoxin-1-2 (C1 and C2), 0.08 µg g(−1) Decarbamoylsaxitoxin (dcSTX) and 0.18 µg g(−1) Gonyautoxin-5 (B1)), being rapidly eliminated (within the first 24 h of depuration), regardless of exposure temperature. Increased temperatures led to significantly higher PST contamination (275 µg STX eq. kg(−1)). During the trial, fish antioxidant enzyme activities (superoxide dismutase, SOD; catalase, CAT; glutathione S-transferase, GST) in both muscle and viscera were affected by temperature, whereas a significant induction of heat shock proteins (HSP70), Ubiquitin (Ub) activity (viscera), and lipid peroxidation (LPO; muscle) was observed under the combination of warming and PST exposure. The differential bioaccumulation and biomarker responses observed highlight the need to further understand the interactive effects between PST and abiotic stressors, to better estimate climate change impacts on HABs events, and to develop mitigation strategies to overcome the potential risks associated with seafood consumption.
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spelling pubmed-66697182019-08-08 Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata) Barbosa, Vera Santos, Marta Anacleto, Patrícia Maulvault, Ana Luísa Pousão-Ferreira, Pedro Costa, Pedro Reis Marques, António Toxins (Basel) Article Warmer seawater temperatures are expected to increase harmful algal blooms (HABs) occurrence, intensity, and distribution. Yet, the potential interactions between abiotic stressors and HABs are still poorly understood from ecological and seafood safety perspectives. The present study aimed to investigate, for the first time, the bioaccumulation/depuration mechanisms and ecotoxicological responses of juvenile gilthead seabream (Sparus aurata) exposed to paralytic shellfish toxins (PST) under different temperatures (18, 21, 24 °C). PST were detected in fish at the peak of the exposure period (day five, 0.22 µg g(−1) N-sulfocarbamoylGonyautoxin-1-2 (C1 and C2), 0.08 µg g(−1) Decarbamoylsaxitoxin (dcSTX) and 0.18 µg g(−1) Gonyautoxin-5 (B1)), being rapidly eliminated (within the first 24 h of depuration), regardless of exposure temperature. Increased temperatures led to significantly higher PST contamination (275 µg STX eq. kg(−1)). During the trial, fish antioxidant enzyme activities (superoxide dismutase, SOD; catalase, CAT; glutathione S-transferase, GST) in both muscle and viscera were affected by temperature, whereas a significant induction of heat shock proteins (HSP70), Ubiquitin (Ub) activity (viscera), and lipid peroxidation (LPO; muscle) was observed under the combination of warming and PST exposure. The differential bioaccumulation and biomarker responses observed highlight the need to further understand the interactive effects between PST and abiotic stressors, to better estimate climate change impacts on HABs events, and to develop mitigation strategies to overcome the potential risks associated with seafood consumption. MDPI 2019-07-13 /pmc/articles/PMC6669718/ /pubmed/31337041 http://dx.doi.org/10.3390/toxins11070408 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barbosa, Vera
Santos, Marta
Anacleto, Patrícia
Maulvault, Ana Luísa
Pousão-Ferreira, Pedro
Costa, Pedro Reis
Marques, António
Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata)
title Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata)
title_full Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata)
title_fullStr Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata)
title_full_unstemmed Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata)
title_short Paralytic Shellfish Toxins and Ocean Warming: Bioaccumulation and Ecotoxicological Responses in Juvenile Gilthead Seabream (Sparus aurata)
title_sort paralytic shellfish toxins and ocean warming: bioaccumulation and ecotoxicological responses in juvenile gilthead seabream (sparus aurata)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669718/
https://www.ncbi.nlm.nih.gov/pubmed/31337041
http://dx.doi.org/10.3390/toxins11070408
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