Cargando…
Codelivery of Genistein and miRNA-29b to A549 Cells Using Aptamer-Hybrid Nanoparticle Bioconjugates
This study aimed to evaluate the anti-cancer effect of a combination therapy of miRNA-29b and genistein loaded in mucin-1 (MUC 1)-aptamer functionalized hybrid nanoparticles in non-small cell lung cancer (NSCLC) A549 cell line. Genistein-miRNA-29b-loaded hybrid nanoparticles (GMLHN) was prepared and...
Autores principales: | Sacko, Koita, Thangavel, Karthik, Shoyele, Sunday A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669731/ https://www.ncbi.nlm.nih.gov/pubmed/31340494 http://dx.doi.org/10.3390/nano9071052 |
Ejemplares similares
-
Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins
por: Perepelyuk, Maryna, et al.
Publicado: (2016) -
siRNA-Encapsulated Hybrid Nanoparticles Target Mutant K-ras and Inhibit Metastatic Tumor Burden in a Mouse Model of Lung Cancer
por: Perepelyuk, Maryna, et al.
Publicado: (2017) -
Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation
por: Dim, Nneka, et al.
Publicado: (2015) -
Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model
por: Perepelyuk, Maryna, et al.
Publicado: (2016) -
Aptamer-functionalized peptide H(3)CR(5)C as a novel nanovehicle for codelivery of fasudil and miRNA-195 targeting hepatocellular carcinoma
por: Liu, Ying, et al.
Publicado: (2016)