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A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment

Radiation therapy is one of the key cancer treatment options. To avoid adverse effects in the healthy tissue, the treatment plan needs to be based on accurate anatomical models of the patient. In this work, an automatic segmentation solution for both female breasts and the heart is constructed using...

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Detalles Bibliográficos
Autores principales: Schreier, Jan, Attanasi, Francesca, Laaksonen, Hannu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669791/
https://www.ncbi.nlm.nih.gov/pubmed/31403032
http://dx.doi.org/10.3389/fonc.2019.00677
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author Schreier, Jan
Attanasi, Francesca
Laaksonen, Hannu
author_facet Schreier, Jan
Attanasi, Francesca
Laaksonen, Hannu
author_sort Schreier, Jan
collection PubMed
description Radiation therapy is one of the key cancer treatment options. To avoid adverse effects in the healthy tissue, the treatment plan needs to be based on accurate anatomical models of the patient. In this work, an automatic segmentation solution for both female breasts and the heart is constructed using deep learning. Our newly developed deep neural networks perform better than the current state-of-the-art neural networks while improving inference speed by an order of magnitude. While manual segmentation by clinicians takes around 20 min, our automatic segmentation takes less than a second with an average of 3 min manual correction time. Thus, our proposed solution can have a huge impact on the workload of clinical staff and on the standardization of care.
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spelling pubmed-66697912019-08-09 A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment Schreier, Jan Attanasi, Francesca Laaksonen, Hannu Front Oncol Oncology Radiation therapy is one of the key cancer treatment options. To avoid adverse effects in the healthy tissue, the treatment plan needs to be based on accurate anatomical models of the patient. In this work, an automatic segmentation solution for both female breasts and the heart is constructed using deep learning. Our newly developed deep neural networks perform better than the current state-of-the-art neural networks while improving inference speed by an order of magnitude. While manual segmentation by clinicians takes around 20 min, our automatic segmentation takes less than a second with an average of 3 min manual correction time. Thus, our proposed solution can have a huge impact on the workload of clinical staff and on the standardization of care. Frontiers Media S.A. 2019-07-25 /pmc/articles/PMC6669791/ /pubmed/31403032 http://dx.doi.org/10.3389/fonc.2019.00677 Text en Copyright © 2019 Schreier, Attanasi and Laaksonen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Schreier, Jan
Attanasi, Francesca
Laaksonen, Hannu
A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment
title A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment
title_full A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment
title_fullStr A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment
title_full_unstemmed A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment
title_short A Full-Image Deep Segmenter for CT Images in Breast Cancer Radiotherapy Treatment
title_sort full-image deep segmenter for ct images in breast cancer radiotherapy treatment
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669791/
https://www.ncbi.nlm.nih.gov/pubmed/31403032
http://dx.doi.org/10.3389/fonc.2019.00677
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