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An Integrated Approach to Characterize Intestinal Metabolites of Four Phenylethanoid Glycosides and Intestinal Microbe-Mediated Antioxidant Activity Evaluation In Vitro Using UHPLC-Q-Exactive High-Resolution Mass Spectrometry and a 1,1-Diphenyl-2-picrylhydrazyl-Based Assay
Intestinal bacteria have a significant role in metabolism and the pharmacologic actions of traditional Chinese medicine active ingredients. Phenylethanoid glycosides (PhGs), as typical phenolic natural products, possess wide bioactivities, but low oral bioavailability. The aim of this work was to el...
Autores principales: | Wang, Xiaoming, Chang, Xiaoyan, Luo, Xiaomei, Su, Meifeng, Xu, Rong, Chen, Jun, Ding, Yi, Shi, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669795/ https://www.ncbi.nlm.nih.gov/pubmed/31402862 http://dx.doi.org/10.3389/fphar.2019.00826 |
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