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Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism

Cellular homeostasis requires the ubiquitin‐dependent degradation of membrane proteins. This was assumed to be mediated exclusively either by endoplasmic reticulum‐associated degradation (ERAD) or by endosomal sorting complexes required for transport (ESCRT)‐dependent lysosomal degradation. We ident...

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Detalles Bibliográficos
Autores principales:	Schmidt, Oliver, Weyer, Yannick, Baumann, Verena, Widerin, Michael A, Eising, Sebastian, Angelova, Mihaela, Schleiffer, Alexander, Kremser, Leopold, Lindner, Herbert, Peter, Matthias, Fröhlich, Florian, Teis, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669922/ https://www.ncbi.nlm.nih.gov/pubmed/31368600 http://dx.doi.org/10.15252/embj.2018101433

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