Arginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA:DNA hybrids

Aberrant transcription‐associated RNA:DNA hybrid (R‐loop) formation often causes catastrophic conflicts during replication, resulting in DNA double‐strand breaks and genomic instability. Preventing such conflicts requires hybrid dissolution by helicases and/or RNase H. Little is known about how such...

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Detalles Bibliográficos
Autores principales: Mersaoui, Sofiane Y, Yu, Zhenbao, Coulombe, Yan, Karam, Martin, Busatto, Franciele F, Masson, Jean‐Yves, Richard, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669924/
https://www.ncbi.nlm.nih.gov/pubmed/31267554
http://dx.doi.org/10.15252/embj.2018100986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669924/
https://www.ncbi.nlm.nih.gov/pubmed/31267554
http://dx.doi.org/10.15252/embj.2018100986

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