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Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface

Designing and fabricating hetero-complexes composed of organic and biological compounds had become an exciting area referring to biological recognition, molecular devices etc. Here, hydrogen-bonded complex of nucleic-acid-base (adenine, A) and fatty-acid (stearic acid, SA) was designed, fabricated a...

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Autores principales: Zhao, Huiling, Yang, Qian, Wang, Zegao, Zhao, Hang, Liu, Bo, Chen, Qianming, Dong, Mingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669938/
https://www.ncbi.nlm.nih.gov/pubmed/31403041
http://dx.doi.org/10.3389/fchem.2019.00513
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author Zhao, Huiling
Yang, Qian
Wang, Zegao
Zhao, Hang
Liu, Bo
Chen, Qianming
Dong, Mingdong
author_facet Zhao, Huiling
Yang, Qian
Wang, Zegao
Zhao, Hang
Liu, Bo
Chen, Qianming
Dong, Mingdong
author_sort Zhao, Huiling
collection PubMed
description Designing and fabricating hetero-complexes composed of organic and biological compounds had become an exciting area referring to biological recognition, molecular devices etc. Here, hydrogen-bonded complex of nucleic-acid-base (adenine, A) and fatty-acid (stearic acid, SA) was designed, fabricated and investigated at liquid/solid interface. The interesting striped-shaped structure composed of SA-A-SA trimers was formed after introducing adenine molecules. Meanwhile, the primary lamella-shape characteristic of the assembly of SA molecules was kept because of the collaboration of non-covalent interactions of molecule-molecule and molecule-substrate. With a series of experimental characterization and theoretical simulation, the origination of the as-prepared 2D hetero-complexes was gradually exhibited from the assembled structures of two building blocks of stearic acid and adenine. Our study provides a blueprint for designing additional multi-component complexes based on the existing molecular assembled architectures.
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spelling pubmed-66699382019-08-09 Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface Zhao, Huiling Yang, Qian Wang, Zegao Zhao, Hang Liu, Bo Chen, Qianming Dong, Mingdong Front Chem Chemistry Designing and fabricating hetero-complexes composed of organic and biological compounds had become an exciting area referring to biological recognition, molecular devices etc. Here, hydrogen-bonded complex of nucleic-acid-base (adenine, A) and fatty-acid (stearic acid, SA) was designed, fabricated and investigated at liquid/solid interface. The interesting striped-shaped structure composed of SA-A-SA trimers was formed after introducing adenine molecules. Meanwhile, the primary lamella-shape characteristic of the assembly of SA molecules was kept because of the collaboration of non-covalent interactions of molecule-molecule and molecule-substrate. With a series of experimental characterization and theoretical simulation, the origination of the as-prepared 2D hetero-complexes was gradually exhibited from the assembled structures of two building blocks of stearic acid and adenine. Our study provides a blueprint for designing additional multi-component complexes based on the existing molecular assembled architectures. Frontiers Media S.A. 2019-07-25 /pmc/articles/PMC6669938/ /pubmed/31403041 http://dx.doi.org/10.3389/fchem.2019.00513 Text en Copyright © 2019 Zhao, Yang, Wang, Zhao, Liu, Chen and Dong. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Zhao, Huiling
Yang, Qian
Wang, Zegao
Zhao, Hang
Liu, Bo
Chen, Qianming
Dong, Mingdong
Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface
title Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface
title_full Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface
title_fullStr Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface
title_full_unstemmed Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface
title_short Fabrication of 2D Hetero-Complexes With Nucleic-Acid-Base Adenine and Fatty-Acid Stearic Acid at Liquid/Solid Interface
title_sort fabrication of 2d hetero-complexes with nucleic-acid-base adenine and fatty-acid stearic acid at liquid/solid interface
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669938/
https://www.ncbi.nlm.nih.gov/pubmed/31403041
http://dx.doi.org/10.3389/fchem.2019.00513
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