Cargando…

Melatonin Prevents Mice Cortical Astrocytes From Hemin-Induced Toxicity Through Activating PKCα/Nrf2/HO-1 Signaling in vitro

Secondary injuries mediated by oxidative stress lead to deterioration of neurological functions after intracerebral hemorrhage (ICH). Cortical astrocytes are among the most important cells in the central nervous system (CNS), and play key roles in maintaining redox homeostasis by providing oxidative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xiao, Xi, Zhiyu, Liang, Huaibin, Sun, Yuhao, Zhong, Zhihong, Wang, Baofeng, Bian, Liuguan, Sun, Qingfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669962/ https://www.ncbi.nlm.nih.gov/pubmed/31404262 http://dx.doi.org/10.3389/fnins.2019.00760

Ejemplares similares

BM-MSC Transplantation Alleviates Intracerebral Hemorrhage-Induced Brain Injury, Promotes Astrocytes Vimentin Expression, and Enhances Astrocytes Antioxidation via the Cx43/Nrf2/HO-1 Axis
por: Chen, Xiao, et al.
Publicado: (2020)

PGE1 triggers Nrf2/HO-1 signal pathway to resist hemin-induced toxicity in mouse cortical neurons
por: Shen, Jiabing, et al.
Publicado: (2021)

Surgical Clipping of Previously Coiled Recurrent Intracranial Aneurysms: A Single-Center Experience
por: Zheng, Yongtao, et al.
Publicado: (2021)

Bone marrow mesenchymal stem cells transplantation alleviates brain injury after intracerebral hemorrhage in mice through the Hippo signaling pathway
por: Chen, Xiao, et al.
Publicado: (2020)

Reoperation for Recurrent and Persistent Cushing’s Disease without Visible MRI Findings
por: Wang, Baofeng, et al.
Publicado: (2022)

NEK2 regulates cellular proliferation and cabergoline sensitivity in pituitary adenomas
por: Jian, Fangfang, et al.
Publicado: (2021)

Correction: Genetic Associations of Angiotensin-Converting Enzyme with Primary Intracerebral Hemorrhage: A Meta-analysis
por: Sun, Yuhao, et al.
Publicado: (2014)

Genetic Associations of Angiotensin-Converting Enzyme with Primary Intracerebral Hemorrhage: A Meta-analysis
por: Sun, Yuhao, et al.
Publicado: (2013)

TSP‐1 is downregulated and inversely correlates with miR‐449c expression in Cushing's disease
por: Ren, Jie, et al.
Publicado: (2019)

Chordoid Glioma of the Third Ventricle: A Case Report and a Treatment Strategy to This Rare Tumor
por: Chen, Xiao, et al.
Publicado: (2020)

Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway
por: Kilic, Ulkan, et al.
Publicado: (2013)

PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis
por: Mylroie, Hayley, et al.
Publicado: (2015)

Melatonin Inhibits Oxidative Stress and Apoptosis in Cryopreserved Ovarian Tissues via Nrf2/HO-1 Signaling Pathway
por: Sun, Tie Cheng, et al.
Publicado: (2020)

Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling
por: Ren, Jie, et al.
Publicado: (2018)

Trends in regional morphological changes in the brain after the resolution of hypercortisolism in Cushing’s disease: a complex phenomenon, not mere partial reversibility
por: Jiang, Hong, et al.
Publicado: (2021)

Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats
por: González-Reyes, Susana, et al.
Publicado: (2013)

Melatonin Act as an Antidepressant via Attenuation of Neuroinflammation by Targeting Sirt1/Nrf2/HO-1 Signaling
por: Ali, Tahir, et al.
Publicado: (2020)

A Selenium Nanocomposite Protects the Mouse Brain from Oxidative Injury Following Intracerebral Hemorrhage
por: Yang, Yong, et al.
Publicado: (2021)

Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis
por: Ma, Hongdong, et al.
Publicado: (2020)

Quinpirole Increases Melatonin-Augmented Pentobarbital Sleep via Cortical ERK, p38 MAPK, and PKC in Mice
por: Hong, Sa-Ik, et al.
Publicado: (2016)

Dataset on characterization of hemin-azide derivative and DNA oligonucleotide-hemin conjugate
por: Kosman, J., et al.
Publicado: (2017)

Astrocyte senescence promotes glutamate toxicity in cortical neurons
por: Limbad, Chandani, et al.
Publicado: (2020)

Melatonin Suppresses LPS-Induced Oxidative Stress in Dendritic Cells for Inflammatory Regulation via the Nrf2/HO-1 Axis
por: Qin, Tao, et al.
Publicado: (2022)

Exogenous hemin improves Cd(2+) tolerance and remediation potential in Vigna radiata by intensifying the HO-1 mediated antioxidant defence system
por: Mahawar, Lovely, et al.
Publicado: (2021)

Sulforaphane Attenuates Contrast-Induced Nephropathy in Rats via Nrf2/HO-1 Pathway
por: Zhao, Zhihong, et al.
Publicado: (2016)

Phycocyanin Protects Against UVB-Induced Apoptosis Through the PKC α/βII-Nrf-2/HO-1 Dependent Pathway in Human Primary Skin Cells
por: Kim, Ki Mo, et al.
Publicado: (2018)

Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway
por: Guo, Ying, et al.
Publicado: (2017)

Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway
por: Shi, Si, et al.
Publicado: (2019)

The Porphyromonas gingivalis Ferric Uptake Regulator Orthologue Binds Hemin and Regulates Hemin-Responsive Biofilm Development
por: Butler, Catherine A., et al.
Publicado: (2014)

Toxic Exposure to Endocrine Disruptors Worsens Parkinson’s Disease Progression through NRF2/HO-1 Alteration
por: D’Amico, Ramona, et al.
Publicado: (2022)

TTB Protects Astrocytes Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury via Activation of Nrf2/HO-1 Signaling Pathway
por: Liu, Liang, et al.
Publicado: (2019)

Comparison of Characteristics and DNAzyme Activity of G4–Hemin Conjugates Obtained via Two Hemin Attachment Methods
por: Kosman, Joanna, et al.
Publicado: (2018)

Reactive Metamizole Metabolites Enhance the Toxicity of Hemin on the ATP Pool in HL60 Cells by Inhibition of Glycolysis
por: Rudin, Deborah, et al.
Publicado: (2020)

Metabolic Heterogeneity of Cerebral Cortical and Cerebellar Astrocytes
por: Sun, Yuanhong, et al.
Publicado: (2023)

New Insights into Hemopexin-Binding to Hemin and Hemoglobin
por: Lechuga, Guilherme C., et al.
Publicado: (2022)

Proteomic analysis of the effect of hemin in breast cancer
por: Coló, G. P., et al.
Publicado: (2023)

Antioxidant Effects of Statins by Modulating Nrf2 and Nrf2/HO-1 Signaling in Different Diseases
por: Mansouri, Atena, et al.
Publicado: (2022)

Hydroxysafflor yellow A improved retinopathy via Nrf2/HO-1 pathway in rats
por: Sun, Zhihui, et al.
Publicado: (2022)

Preparation and Characterization of Tadpole- and Sphere-Shaped Hemin Nanoparticles for Enhanced Solubility
por: Yang, Jie, et al.
Publicado: (2019)

A phenolic amide (LyA) isolated from the fruits of Lycium barbarum protects against cerebral ischemia–reperfusion injury via PKCε/Nrf2/HO-1 pathway
por: Gao, Kai, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4uhm4cqqo2fs1377abhetc60t1