Cargando…

Hypoxia‐induced secretion stimulates breast cancer stem cell regulatory signalling pathways

It is well known that tumour cells are dependent on communication with the tumour microenvironment. Previously, it has been shown that hypoxia (HX) induces pronounced, diverse and direct effects on cancer stem cell (CSC) qualities in different breast cancer subtypes. Here, we describe the mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jacobsson, Hanna, Harrison, Hannah, Hughes, Éamon, Persson, Emma, Rhost, Sara, Fitzpatrick, Paul, Gustafsson, Anna, Andersson, Daniel, Gregersson, Pernilla, Magnusson, Ylva, Ståhlberg, Anders, Landberg, Göran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670019/ https://www.ncbi.nlm.nih.gov/pubmed/31066211 http://dx.doi.org/10.1002/1878-0261.12500

Ejemplares similares

Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion
por: Rhost, Sara, et al.
Publicado: (2018)

Patient-derived scaffolds influence secretion profiles in cancer cells mirroring clinical features and breast cancer subtypes
por: Persson, Emma, et al.
Publicado: (2021)

Identification of Distinct Breast Cancer Stem Cell Populations Based on Single-Cell Analyses of Functionally Enriched Stem and Progenitor Pools
por: Akrap, Nina, et al.
Publicado: (2016)

Characterization of cell-free breast cancer patient-derived scaffolds using liquid chromatography-mass spectrometry/mass spectrometry data and RNA sequencing data
por: Landberg, Göran, et al.
Publicado: (2020)

Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancer
por: Berger, Karoline, et al.
Publicado: (2021)

The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer
por: Walsh, Claire A., et al.
Publicado: (2020)

Patient-derived scaffolds as a drug-testing platform for endocrine therapies in breast cancer
por: Gustafsson, Anna, et al.
Publicado: (2021)

Cellular organization and molecular differentiation model of breast cancer-associated fibroblasts
por: Busch, Susann, et al.
Publicado: (2017)

Breast Cancer Patient-Derived Scaffolds Can Expose Unique Individual Cancer Progressing Properties of the Cancer Microenvironment Associated with Clinical Characteristics
por: Garre, Elena, et al.
Publicado: (2022)

Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells
por: Jonasson, Emma, et al.
Publicado: (2019)

Properties of targeted preamplification in DNA and cDNA quantification
por: Andersson, Daniel, et al.
Publicado: (2015)

Breast cancer patient‐derived scaffolds as a tool to monitor chemotherapy responses in human tumor microenvironments
por: Leiva, Maria Carmen, et al.
Publicado: (2020)

Identification of inhibitors regulating cell proliferation and FUS-DDIT3 expression in myxoid liposarcoma using combined DNA, mRNA, and protein analyses
por: Svec, David, et al.
Publicado: (2018)

5-fluorouracil treatment of patient-derived scaffolds from colorectal cancer reveal clinically critical information
por: Salerno, Simona, et al.
Publicado: (2022)

The Effect of Hypoxic and Normoxic Culturing Conditions in Different Breast Cancer 3D Model Systems
por: Svanström, Andreas, et al.
Publicado: (2021)

LiPLike: towards gene regulatory network predictions of high certainty
por: Magnusson, Rasmus, et al.
Publicado: (2020)

A comparison study of insulin concentrations in follicular fluid, serum and in vitro-production of bovine embryos – risks of generating unfavourable metabolic conditions during early development
por: Laskowski, Denise, et al.
Publicado: (2015)

Insulin concentrations used in in vitro embryo production systems: a pilot study on insulin stability with an emphasis on concentrations measured in vivo
por: Laskowski, Denise, et al.
Publicado: (2016)

Cell Cycle and Cell Size Dependent Gene Expression Reveals Distinct Subpopulations at Single-Cell Level
por: Dolatabadi, Soheila, et al.
Publicado: (2017)

Patient‐derived scaffolds as a model of colorectal cancer
por: Parkinson, Gabrielle T., et al.
Publicado: (2020)

Unravelling the biological secrets of microchimerism by single-cell analysis
por: Ståhlberg, Anders, et al.
Publicado: (2017)

Intensive weight gain therapy in patients with anorexia nervosa results in improved serum tartrate-resistant acid phosphatase (TRAP) 5a and 5b isoform protein levels
por: Patlaka, Christina, et al.
Publicado: (2019)

Hyperinsulinemia during in vitro oocyte maturation changes gene expression of insulin signaling in bovine Day-8 embryos
por: Laskowski, Denise, et al.
Publicado: (2015)

ComHub: Community predictions of hubs in gene regulatory networks
por: Åkesson, Julia, et al.
Publicado: (2021)

Hypoxia, Snail and incomplete epithelial–mesenchymal transition in breast cancer
por: Lundgren, K, et al.
Publicado: (2009)

3D Printed Nanocellulose Scaffolds as a Cancer Cell Culture Model System
por: Rosendahl, Jennifer, et al.
Publicado: (2021)

Distinct Cytoplasmic and Nuclear Functions of the Stress Induced Protein DDIT3/CHOP/GADD153
por: Jauhiainen, Alexandra, et al.
Publicado: (2012)

JAK–STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid liposarcoma
por: Dolatabadi, Soheila, et al.
Publicado: (2019)

Prediction and modeling of pre-analytical sampling errors as a strategy to improve plasma NMR metabolomics data
por: Brunius, Carl, et al.
Publicado: (2017)

Revealing cell cycle control by combining model-based detection of periodic expression with novel cis-regulatory descriptors
por: Andersson, Claes R, et al.
Publicado: (2007)

Etiology and antimicrobial susceptibility of udder pathogens from cases of subclinical mastitis in dairy cows in Sweden
por: Persson, Ylva, et al.
Publicado: (2011)

N-CAM Exhibits a Regulatory Function in Pathological Angiogenesis in Oxygen Induced Retinopathy
por: Håkansson, Joakim, et al.
Publicado: (2011)

Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling
por: Harrison, Hannah, et al.
Publicado: (2013)

Impact of region-of-interest method on quantitative analysis of DTI data in the optic tracts
por: Lilja, Ylva, et al.
Publicado: (2016)

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
por: Andersson, Mattias K, et al.
Publicado: (2008)

Tissue Factor promotes breast cancer stem cell activity in vitro
por: Shaker, Hudhaifah, et al.
Publicado: (2016)

Proteoglycan profiling of human, rat and mouse insulin-secreting cells
por: Nikpour, Mahnaz, et al.
Publicado: (2021)

Mast Cell Survival and Mediator Secretion in Response to Hypoxia
por: Gulliksson, Magdalena, et al.
Publicado: (2010)

Overweight and obesity during adolescence increases the risk of renal cell carcinoma
por: Landberg, Anna, et al.
Publicado: (2019)

Global preamplification simplifies targeted mRNA quantification
por: Kroneis, Thomas, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pkfvbcjs6bgtol52nub5el49h0