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Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses
The ability to predict responsiveness to drugs in individual patients is limited. We hypothesized that integrating molecular information from databases would yield predictions that could be experimentally tested to develop transcriptomic signatures for specific drugs. We analyzed lung adenocarcinoma...
Autores principales: | Tavassoly, Iman, Hu, Yuan, Zhao, Shan, Mariottini, Chiara, Boran, Aislyn, Chen, Yibang, Li, Lisa, Tolentino, Rosa E., Jayaraman, Gomathi, Goldfarb, Joseph, Gallo, James, Iyengar, Ravi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670022/ https://www.ncbi.nlm.nih.gov/pubmed/31116490 http://dx.doi.org/10.1002/1878-0261.12521 |
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