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Cathepsin L-mediated resistance of paclitaxel and cisplatin is mediated by distinct regulatory mechanisms

BACKGROUND: Cathepsin L (CTSL) is a cysteine protease known to have important roles in regulating cancer cellular resistance to chemotherapy. However mechanism underlying which regulates CTSL-mediated drug resistance remain largely unknown. METHODS: We used NSCLC cell lines: A549, A549/TAX (paclitax...

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Detalles Bibliográficos
Autores principales:	Zhao, Yifan, Shen, Xiao, Zhu, Ying, Wang, Anqi, Xiong, Yajie, Wang, Long, Fei, Yao, Wang, Yan, Wang, Wenjuan, Lin, Fang, Liang, Zhongqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670178/ https://www.ncbi.nlm.nih.gov/pubmed/31370861 http://dx.doi.org/10.1186/s13046-019-1299-4

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