Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers

BACKGROUND: Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome (pSS). Non-SS sicca subjects, an underexplored group in relation to pSS, display similar sicca s...

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Detalles Bibliográficos
Autores principales: Aqrawi, Lara A., Galtung, Hilde Kanli, Guerreiro, Eduarda M., Øvstebø, Reidun, Thiede, Bernd, Utheim, Tor Paaske, Chen, Xiangjun, Utheim, Øygunn Aass, Palm, Øyvind, Skarstein, Kathrine, Jensen, Janicke Liaaen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670195/
https://www.ncbi.nlm.nih.gov/pubmed/31366407
http://dx.doi.org/10.1186/s13075-019-1961-4

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