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Distribution of CYP2D6 polymorphism in the Middle Eastern region

Cytochrome P450 2D6 (CYP2D6) is an important drug-metabolizing enzyme involved in the pharmacokinetic metabolism of drugs. CYP2D6 gene is highly polymorphic, and the combination of its different alleles yields different phenotypes including extensive metabolizer (EM), intermediate metabolizer (IM),...

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Detalles Bibliográficos
Autores principales: Khalaj, Zahra, Baratieh, Zohreh, Nikpour, Parvaneh, Khanahmad, Hossein, Mokarian, Fariborz, Salehi, Rasoul, Salehi, Mansoor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670283/
https://www.ncbi.nlm.nih.gov/pubmed/31523247
http://dx.doi.org/10.4103/jrms.JRMS_1076_18