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Successful application of prime and pull strategy for a therapeutic HSV vaccine

One promising approach for a herpes simplex virus vaccine uses a vaccine to prime and a chemoattractant to pull immune cells into the genital tract. We evaluated subunit vaccines (prime) and imiquimod (pull) in the guinea pig (gp) model of recurrent Herpes simplex virus type-2 (HSV-2). Following vag...

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Detalles Bibliográficos
Autores principales:	Bernstein, David I., Cardin, Rhonda D., Bravo, Fernando J., Awasthi, Sita, Lu, Peiwen, Pullum, Derek A., Dixon, David A., Iwasaki, Akiko, Friedman, Harvey M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671986/ https://www.ncbi.nlm.nih.gov/pubmed/31396405 http://dx.doi.org/10.1038/s41541-019-0129-1

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