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Novel CB1-ligands maintain homeostasis of the endocannabinoid system in ω3- and ω6-long-chain-PUFA deficiency

Mammalian ω3- and ω6-PUFAs are synthesized from essential fatty acids (EFAs) or supplied by the diet. PUFAs are constitutive elements of membrane architecture and precursors of lipid signaling molecules. EFAs and long-chain (LC)-PUFAs are precursors in the synthesis of endocannabinoid ligands of G(i...

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Detalles Bibliográficos
Autores principales: Hammels, Ina, Binczek, Erika, Schmidt-Soltau, Inga, Jenke, Britta, Thomas, Andreas, Vogel, Matthias, Thevis, Mario, Filipova, Dilyana, Papadopoulos, Symeon, Stoffel, Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672042/
https://www.ncbi.nlm.nih.gov/pubmed/31167809
http://dx.doi.org/10.1194/jlr.M094664