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Novel CB1-ligands maintain homeostasis of the endocannabinoid system in ω3- and ω6-long-chain-PUFA deficiency
Mammalian ω3- and ω6-PUFAs are synthesized from essential fatty acids (EFAs) or supplied by the diet. PUFAs are constitutive elements of membrane architecture and precursors of lipid signaling molecules. EFAs and long-chain (LC)-PUFAs are precursors in the synthesis of endocannabinoid ligands of G(i...
Autores principales: | Hammels, Ina, Binczek, Erika, Schmidt-Soltau, Inga, Jenke, Britta, Thomas, Andreas, Vogel, Matthias, Thevis, Mario, Filipova, Dilyana, Papadopoulos, Symeon, Stoffel, Wilhelm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672042/ https://www.ncbi.nlm.nih.gov/pubmed/31167809 http://dx.doi.org/10.1194/jlr.M094664 |
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