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The orphan nuclear receptor SHP regulates ER stress response by inhibiting XBP1s degradation

The orphan nuclear receptor SHP (small heterodimer partner) is a well-known transcriptional corepressor of bile acid and lipid metabolism in the liver; however, its function in other tissues is poorly understood. Here, we report an unexpected role for SHP in the exocrine pancreas as a modulator of t...

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Detalles Bibliográficos
Autores principales:	Sun, Shengyi, Kelekar, Sherwin, Kliewer, Steven A., Mangelsdorf, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672048/ https://www.ncbi.nlm.nih.gov/pubmed/31296559 http://dx.doi.org/10.1101/gad.326868.119

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