Integrative analysis of transcriptome-wide association study and gene expression profiling identifies candidate genes associated with stroke

BACKGROUND: Stroke is a major public health burden worldwide. Although genetic variation is known to play a role in the pathogenesis of stroke, the specific pathogenic mechanisms are still unclear. Transcriptome-wide association studies (TWAS) is a powerful approach to prioritize candidate risk gene...

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Detalles Bibliográficos
Autores principales: Yang, Jian, Yan, Bin, Fan, Yajuan, Yang, Lihong, Zhao, Binbin, He, Xiaoyan, Ma, Qingyan, Wang, Wei, Bai, Ling, Zhang, Feng, Ma, Xiancang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673425/
https://www.ncbi.nlm.nih.gov/pubmed/31392102
http://dx.doi.org/10.7717/peerj.7435

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