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Partial vaginal expulsion of a leiomyosarcoma

Uterine sarcomas are an uncommon and heterogeneous group of tumors that account for 3-7% of the malignant neoplasms of the uterus and approximately 1% of all malignant tumors of the female genital system. The main clinical manifestations are abnormal uterine bleeding in pre- or postmenopausal women....

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Autores principales: Yokochi, Kaori, Lorenzi, Noely Paula Cristina, Simões, Ricardo dos Santos, Fonseca, Leonardo Gomes, de Lima, Patrícia Picciarelli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673685/
https://www.ncbi.nlm.nih.gov/pubmed/31528608
http://dx.doi.org/10.4322/acr.2013.018
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author Yokochi, Kaori
Lorenzi, Noely Paula Cristina
Simões, Ricardo dos Santos
Fonseca, Leonardo Gomes
de Lima, Patrícia Picciarelli
author_facet Yokochi, Kaori
Lorenzi, Noely Paula Cristina
Simões, Ricardo dos Santos
Fonseca, Leonardo Gomes
de Lima, Patrícia Picciarelli
author_sort Yokochi, Kaori
collection PubMed
description Uterine sarcomas are an uncommon and heterogeneous group of tumors that account for 3-7% of the malignant neoplasms of the uterus and approximately 1% of all malignant tumors of the female genital system. The main clinical manifestations are abnormal uterine bleeding in pre- or postmenopausal women. Pelvic pain, abdominal distension, urinary urgency, and profuse and fetid leukorrhea are other frequent complaints. The authors present a case of a 48-year-old patient that was in amenorrhea for 2 years, who sought treatment for vaginal bleeding. On physical examination, the abdomen was distended, painful in the hypogastrium and upon examination of the external genitalia, it was observed the exteriorization of an amorphous “mass”. The patient was submitted to uterine curettage. The results of the histological examination revealed leiomyosarcoma. Staging workup showed an enlarged uterus with endometrial lesion, and non-calcified pulmonary nodules. The patient underwent a pan-hysterectomy and chemotherapy, and is under oncologic treatment. The authors call attention for the unusual form of presentation of this entity.
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spelling pubmed-66736852019-09-16 Partial vaginal expulsion of a leiomyosarcoma Yokochi, Kaori Lorenzi, Noely Paula Cristina Simões, Ricardo dos Santos Fonseca, Leonardo Gomes de Lima, Patrícia Picciarelli Autops Case Rep Article / Clinical Case Reports Uterine sarcomas are an uncommon and heterogeneous group of tumors that account for 3-7% of the malignant neoplasms of the uterus and approximately 1% of all malignant tumors of the female genital system. The main clinical manifestations are abnormal uterine bleeding in pre- or postmenopausal women. Pelvic pain, abdominal distension, urinary urgency, and profuse and fetid leukorrhea are other frequent complaints. The authors present a case of a 48-year-old patient that was in amenorrhea for 2 years, who sought treatment for vaginal bleeding. On physical examination, the abdomen was distended, painful in the hypogastrium and upon examination of the external genitalia, it was observed the exteriorization of an amorphous “mass”. The patient was submitted to uterine curettage. The results of the histological examination revealed leiomyosarcoma. Staging workup showed an enlarged uterus with endometrial lesion, and non-calcified pulmonary nodules. The patient underwent a pan-hysterectomy and chemotherapy, and is under oncologic treatment. The authors call attention for the unusual form of presentation of this entity. São Paulo, SP: Universidade de São Paulo, Hospital Universitário 2013-06-30 /pmc/articles/PMC6673685/ /pubmed/31528608 http://dx.doi.org/10.4322/acr.2013.018 Text en Autopsy and Case Reports. ISSN 2236-1960. Copyright © 2013. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the article is properly cited.
spellingShingle Article / Clinical Case Reports
Yokochi, Kaori
Lorenzi, Noely Paula Cristina
Simões, Ricardo dos Santos
Fonseca, Leonardo Gomes
de Lima, Patrícia Picciarelli
Partial vaginal expulsion of a leiomyosarcoma
title Partial vaginal expulsion of a leiomyosarcoma
title_full Partial vaginal expulsion of a leiomyosarcoma
title_fullStr Partial vaginal expulsion of a leiomyosarcoma
title_full_unstemmed Partial vaginal expulsion of a leiomyosarcoma
title_short Partial vaginal expulsion of a leiomyosarcoma
title_sort partial vaginal expulsion of a leiomyosarcoma
topic Article / Clinical Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673685/
https://www.ncbi.nlm.nih.gov/pubmed/31528608
http://dx.doi.org/10.4322/acr.2013.018
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