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Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering

Myosin VI plays crucial roles in diverse cellular processes. In autophagy, Myosin VI can facilitate the maturation of autophagosomes through interactions with Tom1 and the autophagy receptors, Optineurin, NDP52 and TAX1BP1. Here, we report the high-resolution crystal structure of the C-terminal carg...

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Detalles Bibliográficos
Autores principales:	Hu, Shichen, Guo, Yujiao, Wang, Yingli, Li, Ying, Fu, Tao, Zhou, Zixuan, Wang, Yaru, Liu, Jianping, Pan, Lifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673701/ https://www.ncbi.nlm.nih.gov/pubmed/31371777 http://dx.doi.org/10.1038/s41467-019-11481-6

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