14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking

Receptor trafficking is pivotal for the temporal and spatial control of GPCR signaling and is regulated by multiple cellular proteins. We provide evidence that GPCRs interact with 14-3-3 signal adaptor/scaffold proteins and that this interaction regulates receptor trafficking in two ways. We found G...

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Detalles Bibliográficos
Autores principales: Yuan, Luwa, Barbash, Shahar, Kongsamut, Sathapana, Eishingdrelo, Alex, Sakmar, Thomas P., Eishingdrelo, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673703/
https://www.ncbi.nlm.nih.gov/pubmed/31371790
http://dx.doi.org/10.1038/s41598-019-47478-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673703/
https://www.ncbi.nlm.nih.gov/pubmed/31371790
http://dx.doi.org/10.1038/s41598-019-47478-w

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