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Gene-edited murine cell lines for propagation of chronic wasting disease prions

Prions cause fatal infectious neurodegenerative diseases in humans and animals. Cell culture models are essential for studying the molecular biology of prion propagation. Defining such culture models is mostly a random process, includes extensive subcloning, and for many prion diseases few or no mod...

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Detalles Bibliográficos
Autores principales: Walia, Rupali, Ho, Cheng Ching, Lee, Chi, Gilch, Sabine, Schatzl, Hermann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673760/
https://www.ncbi.nlm.nih.gov/pubmed/31371793
http://dx.doi.org/10.1038/s41598-019-47629-z