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Gene-edited murine cell lines for propagation of chronic wasting disease prions
Prions cause fatal infectious neurodegenerative diseases in humans and animals. Cell culture models are essential for studying the molecular biology of prion propagation. Defining such culture models is mostly a random process, includes extensive subcloning, and for many prion diseases few or no mod...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673760/ https://www.ncbi.nlm.nih.gov/pubmed/31371793 http://dx.doi.org/10.1038/s41598-019-47629-z |