Targeted sequencing of candidate genes of dyslipidemia in Punjabi Sikhs: Population-specific rare variants in GCKR promote ectopic fat deposition

Dyslipidemia is a well-established risk factor for cardiovascular diseases. Although, advances in genome-wide technologies have enabled the discovery of hundreds of genes associated with blood lipid phenotypes, most of the heritability remains unexplained. Here we performed targeted resequencing of...

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Detalles Bibliográficos
Autores principales: Sanghera, Dharambir K., Hopkins, Ruth, Malone-Perez, Megan W., Bejar, Cynthia, Tan, Chengcheng, Mussa, Huda, Whitby, Paul, Fowler, Ben, Rao, Chinthapally V., Fung, KarMing A., Lightfoot, Stan, Frazer, J. Kimble
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675050/
https://www.ncbi.nlm.nih.gov/pubmed/31369557
http://dx.doi.org/10.1371/journal.pone.0211661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675050/
https://www.ncbi.nlm.nih.gov/pubmed/31369557
http://dx.doi.org/10.1371/journal.pone.0211661

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