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TP53 codon 72 polymorphism is associated with FGFR3 and RAS mutation in non-muscle-invasive bladder cancer

OBJECTIVE: TP53, a well-known tumor-suppressor gene in bladder carcinogenesis, has a functional single-nucleotide polymorphism on codon 72. The aim of this study was to elucidate the association between TP53 codon 72 polymorphism and somatic mutations in bladder cancer. MATERIAL AND METHODS: Germlin...

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Detalles Bibliográficos
Autores principales:	Kawahara, Takashi, Kojima, Takahiro, Kandori, Shuya, Kurobe, Masahiro, Yoshino, Takayuki, Kimura, Tomokazu, Nagumo, Yoshiyuki, Ishituka, Ryutaro, Mitsuzuka, Koji, Narita, Shintaro, Kobayashi, Takashi, Matsui, Yoshiyuki, Ogawa, Osamu, Sugimoto, Mikio, Miyazaki, Jun, Nishiyama, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675066/ https://www.ncbi.nlm.nih.gov/pubmed/31369573 http://dx.doi.org/10.1371/journal.pone.0220173

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