Pharmacological inhibition of NPY receptors illustrates dissociable features of experimental colitis in the mouse DSS model: Implications for preclinical evaluation of efficacy in an inflammatory bowel disease model

Administration of dextran sodium sulfate (DSS) to rodents at varying concentrations and exposure times is commonly used to model human inflammatory bowel disease (IBD). Currently, the criteria used to assess IBD-like pathology seldom include surrogate measures of visceral pain. Thus, we sought to st...

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Detalles Bibliográficos
Autores principales: Ruiz, Henry H., Becker, Stephanie, Bai, Yu, Cortes-Burgos, Luz A., Eckersdorff, Melissa M., Macdonald, Lynn E., Croll, Susan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675069/
https://www.ncbi.nlm.nih.gov/pubmed/31369588
http://dx.doi.org/10.1371/journal.pone.0220156

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