Cargando…

High NDRG3 expression facilitates HCC metastasis by promoting nuclear translocation of β-catenin

NDRG1 has been reported to exert pivotal roles in tumor progression and metastasis via Wnt/β-catenin signaling pathway. However, little is known about the role of NDRG3 in hepatocarcinogenesis despite its classification in the same subfamily of NDRG1. The present study was aimed to characterize the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, JiKui, Zheng, HongZhen, Yuan, LingYan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675243/ https://www.ncbi.nlm.nih.gov/pubmed/31072445 http://dx.doi.org/10.5483/BMBRep.2019.52.7.201

Ejemplares similares

MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin
por: Tian, Guang-Ang, et al.
Publicado: (2020)

The metastasis suppressor, NDRG1, inhibits “stemness” of colorectal cancer via down-regulation of nuclear β-catenin and CD44
por: Wangpu, Xiongzhi, et al.
Publicado: (2015)

TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC
por: Tang, Bufu, et al.
Publicado: (2023)

CAV1 Promotes HCC Cell Progression and Metastasis through Wnt/β-Catenin Pathway
por: Yu, Hongxiu, et al.
Publicado: (2014)

NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia
por: Wang, Xiao, et al.
Publicado: (2023)

Differential Nuclear Translocation and Transactivation Potential of β-Catenin and Plakoglobin
por: Simcha, Inbal, et al.
Publicado: (1998)

NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation
por: Li, Ting, et al.
Publicado: (2018)

BRF2 is mediated by microRNA-409-3p and promotes invasion and metastasis of HCC through the Wnt/β-catenin pathway
por: Chang, Jian-Hua, et al.
Publicado: (2023)

Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocation
por: Zhang, Yue, et al.
Publicado: (2018)

Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis
por: Liu, Kaisheng, et al.
Publicado: (2016)

CUEDC2 Drives β-Catenin Nuclear Translocation and Promotes Triple-Negative Breast Cancer Tumorigenesis
por: Han, Shuyan, et al.
Publicado: (2022)

Nuclear translocation of beta-catenin in colorectal cancer
por: Kobayashi, M, et al.
Publicado: (2000)

miR-1254 induced by NESG1 inactivates HDGF/DDX5-stimulated nuclear translocation of β-catenin and suppresses NPC metastasis
por: Cheng, Chao, et al.
Publicado: (2021)

NDRG1 promotes growth of hepatocellular carcinoma cells by directly interacting with GSK-3β and Nur77 to prevent β-catenin degradation
por: Lu, Wen-Jing, et al.
Publicado: (2015)

UBE2T promotes β‐catenin nuclear translocation in hepatocellular carcinoma through MAPK/ERK‐dependent activation
por: Lioulia, Elisavet, et al.
Publicado: (2022)

IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin
por: Tian, Miao, et al.
Publicado: (2020)

NDRG2 inhibition facilitates angiogenesis of hepatocellular carcinoma
por: Wang, Jianlong, et al.
Publicado: (2021)

Promotion of growth factor signaling as a critical function of β-catenin during HCC progression
por: Kim, Eunsun, et al.
Publicado: (2019)

β-catenin nuclear translocation induced by HIF-1α overexpression leads to the radioresistance of prostate cancer
por: Luo, Yong, et al.
Publicado: (2018)

Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation
por: Kimura, Ryota, et al.
Publicado: (2013)

Chronic alcohol exposure promotes HCC stemness and metastasis through β-catenin/miR-22-3p/TET2 axis
por: Chen, Danlei, et al.
Publicado: (2021)

NDRG2 expression decreases with tumor stages and regulates TCF/β-catenin signaling in human colon carcinoma
por: Kim, Young-Jun, et al.
Publicado: (2009)

HBX-induced miR-5188 impairs FOXO1 to stimulate β-catenin nuclear translocation and promotes tumor stemness in hepatocellular carcinoma
por: Lin, Xian, et al.
Publicado: (2019)

Roles of lncRNAs Mediating Wnt/β-Catenin Signaling in HCC
por: Xu, Yating, et al.
Publicado: (2022)

Claudin‐2 promotes colorectal cancer growth and metastasis by suppressing NDRG1 transcription
por: Wei, Mingtian, et al.
Publicado: (2021)

FGF9 Recruits β‐Catenin to Increase Hepatic ECM Synthesis and Promote NASH‐Driven HCC
por: Zhang, Lei, et al.
Publicado: (2023)

Apolipoprotein(a) stimulates nuclear translocation of β-catenin: a novel pathogenic mechanism for lipoprotein(a)
por: Cho, Taewoo, et al.
Publicado: (2013)

Critical roles of SMYD2-mediated β-catenin methylation for nuclear translocation and activation of Wnt signaling
por: Deng, Xiaolan, et al.
Publicado: (2017)

Author Correction: IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin
por: Tian, Miao, et al.
Publicado: (2023)

Oncogenic MNK signalling regulates the metastasis suppressor NDRG1
por: Tian, Shuye, et al.
Publicado: (2017)

A lignan induces lysosomal dependent degradation of FoxM1 protein to suppress β-catenin nuclear translocation
por: Dong, Guang-zhi, et al.
Publicado: (2017)

Akt1 inhibition promotes breast cancer metastasis through EGFR-mediated β-catenin nuclear accumulation
por: Li, Wei, et al.
Publicado: (2018)

SYVN1 ubiquitinates FoxO1 to induce β-catenin nuclear translocation, PD-L1-mediated metastasis, and immune evasion of hepatocellular carcinoma
por: Xie, Wei, et al.
Publicado: (2023)

Forkhead Box Protein J1 (FOXJ1) is Overexpressed in Colorectal Cancer and Promotes Nuclear Translocation of β-Catenin in SW620 Cells
por: Liu, Kuiliang, et al.
Publicado: (2017)

Nuclear Translocation of β-Catenin during Mesenchymal Stem Cells Differentiation into Hepatocytes Is Associated with a Tumoral Phenotype
por: Herencia, Carmen, et al.
Publicado: (2012)

Nuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone
por: Kimura, Atsushi, et al.
Publicado: (2022)

N‐glycosylation by N‐acetylglucosaminyltransferase V enhances the interaction of CD147/basigin with integrin β1 and promotes HCC metastasis
por: Cui, Jian, et al.
Publicado: (2018)

UBQLN4 promotes progression of HCC via activating wnt-β-catenin pathway and is regulated by miR-370
por: Yu, Yan, et al.
Publicado: (2020)

Cooperation Between the NRF2 Pathway and Oncogenic β‐catenin During HCC Tumorigenesis
por: Savall, Mathilde, et al.
Publicado: (2021)

γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin
por: Morgan, R G, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_409t5ffi856ttb4cmt4j82lmja