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Expression and secretion of CXCL12 are enhanced in autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD), one of the most common human monogenic diseases (frequency of 1/1000-1/400), is characterized by numerous fluid-filled renal cysts (RCs). Inactivation of the PKD1 or PKD2 gene by germline and somatic mutations is necessary for cyst formation in A...

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Detalles Bibliográficos
Autores principales:	Kim, Hyunho, Sung, Jinmo, Kim, Hyunsuk, Ryu, Hyunjin, Park, Hayne Cho, Oh, Yun Kyu, Lee, Hyun-Seob, Oh, Kook-Hwan, Ahn, Curie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675246/ https://www.ncbi.nlm.nih.gov/pubmed/31186083 http://dx.doi.org/10.5483/BMBRep.2019.52.7.112

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