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Mass spectrometry–driven exploration reveals nuances of neoepitope-driven tumor rejection

Neoepitopes are the only truly tumor-specific antigens. Although potential neoepitopes can be readily identified using genomics, the neoepitopes that mediate tumor rejection constitute a small minority, and there is little consensus on how to identify them. Here, for the first time to our knowledge,...

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Detalles Bibliográficos
Autores principales: Ebrahimi-Nik, Hakimeh, Michaux, Justine, Corwin, William L., Keller, Grant L.J., Shcheglova, Tatiana, Pak, HuiSong, Coukos, George, Baker, Brian M., Mandoiu, Ion I., Bassani-Sternberg, Michal, Srivastava, Pramod K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675551/
https://www.ncbi.nlm.nih.gov/pubmed/31219806
http://dx.doi.org/10.1172/jci.insight.129152