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DNA crosslink repair safeguards genomic stability during pre-meiotic germ cell development
Germline de novo mutations are the basis of evolutionary diversity but also of genetic disease. However, the molecular origin, mechanisms and timing of germline mutagenesis are not fully understood. Here, we define a fundamental role for DNA interstrand crosslink repair in the germline. This repair...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675612/ https://www.ncbi.nlm.nih.gov/pubmed/31367016 http://dx.doi.org/10.1038/s41588-019-0471-2 |