Engineering macrophages to phagocytose cancer cells by blocking the CD47/SIRPɑ axis

The use of immunotherapy has achieved great advances in the treatment of cancer. Macrophages play a pivotal role in the immune defense system, serving both as phagocytes (removal of pathogens and cancer cells) and as antigen‐presenting cells (activation of T cells). However, research regarding tumor...

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Detalles Bibliográficos
Autores principales: Yang, Hongcheng, Shao, Ruoyang, Huang, Hongxin, Wang, Xinlong, Rong, Zhili, Lin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675709/
https://www.ncbi.nlm.nih.gov/pubmed/31183992
http://dx.doi.org/10.1002/cam4.2332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675709/
https://www.ncbi.nlm.nih.gov/pubmed/31183992
http://dx.doi.org/10.1002/cam4.2332

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