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Detection of Circulating Tumor DNA with a Single-Molecule Sequencing Analysis Validated for Targeted and Immunotherapy Selection

INTRODUCTION: Comprehensive genetic cancer profiling using circulating tumor DNA has enabled the detection of National Comprehensive Cancer Network (NCCN) guideline-recommended somatic alterations from a single, non-invasive blood draw. However, reliably detecting somatic variants at low variant all...

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Detalles Bibliográficos
Autores principales: Atkins, Alexander, Gupta, Pratyush, Zhang, Bing Melody, Tsai, Wen-Sy, Lucas, Julian, Javey, Manana, Vora, Anagh, Mei, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675782/
https://www.ncbi.nlm.nih.gov/pubmed/31209714
http://dx.doi.org/10.1007/s40291-019-00406-0