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Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling

Antiretroviral therapy extends survival but does not eliminate HIV from its cellular reservoirs. Between immune and stromal cells in the tissue microenvironment, a dynamic intercellular communication might influence host viral immune responses via intercellular transfer of extracellular vehicles (EV...

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Detalles Bibliográficos
Autores principales: Yuan, Zhihong, Petree, Jessica R., Lee, F. Eun-Hyung, Fan, Xian, Salaita, Khalid, Guidot, David M., Sadikot, Ruxana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675785/
https://www.ncbi.nlm.nih.gov/pubmed/31371699
http://dx.doi.org/10.1038/s41419-019-1803-y

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