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Programmed −2/−1 Ribosomal Frameshifting in Simarteriviruses: an Evolutionarily Conserved Mechanism

The −2/−1 programmed ribosomal frameshifting (−2/−1 PRF) mechanism in porcine reproductive and respiratory syndrome virus (PRRSV) leads to the translation of two additional viral proteins, nonstructural protein 2TF (nsp2TF) and nsp2N. This −2/−1 PRF mechanism is transactivated by a viral protein, ns...

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Detalles Bibliográficos
Autores principales:	Li, Yanhua, Firth, Andrew E., Brierley, Ian, Cai, Yingyun, Napthine, Sawsan, Wang, Tao, Yan, Xingyu, Kuhn, Jens H., Fang, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675879/ https://www.ncbi.nlm.nih.gov/pubmed/31167906 http://dx.doi.org/10.1128/JVI.00370-19

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