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Sister DNA Entrapment between Juxtaposed Smc Heads and Kleisin of the Cohesin Complex
Cohesin entraps sister DNAs within tripartite rings created by pairwise interactions between Smc1, Smc3, and Scc1. Because Smc1/3 ATPase heads can also interact with each other, cohesin rings have the potential to form a variety of sub-compartments. Using in vivo cysteine cross-linking, we show that...
Autores principales: | Chapard, Christophe, Jones, Robert, van Oepen, Till, Scheinost, Johanna C., Nasmyth, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675936/ https://www.ncbi.nlm.nih.gov/pubmed/31201089 http://dx.doi.org/10.1016/j.molcel.2019.05.023 |
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