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Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in Apc (Δ716) mutant mice

Iodothyronine deiodinase 2 (DIO2) converts the prohormone thyroxine (T4) to bioactive T3 in peripheral tissues and thereby regulates local thyroid hormone (TH) levels. Although epidemiologic studies suggest the contribution of TH to the progression of colorectal cancer (CRC), the role of DIO2 in CRC...

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Detalles Bibliográficos
Autores principales:	Kojima, Yasushi, Kondo, Yuriko, Fujishita, Teruaki, Mishiro‐Sato, Emi, Kajino‐Sakamoto, Rie, Taketo, Makoto Mark, Aoki, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676103/ https://www.ncbi.nlm.nih.gov/pubmed/31215118 http://dx.doi.org/10.1111/cas.14100

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