Cargando…

Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA‐A24‐positive pancreatic adenocarcinoma

The prognosis of advanced pancreatic adenocarcinoma is still extremely poor. This study sought to determine the efficacy of, and immunological response to, peptide vaccination therapy in patients with this disease. In this multicenter randomized phase II study, patients with advanced pancreatic aden...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shima, Hiroaki, Tsurita, Giichiro, Wada, Satoshi, Hirohashi, Yoshihiko, Yasui, Hiroshi, Hayashi, Hiroshi, Miyakoshi, Takashi, Watanabe, Kazue, Murai, Aiko, Asanuma, Hiroko, Tokita, Serina, Kubo, Terufumi, Nakatsugawa, Munehide, Kanaseki, Takayuki, Tsukahara, Tomohide, Nakae, Yutaka, Sugita, Osamu, Ito, Yoichi M., Ota, Yasunori, Kimura, Yasutoshi, Kutomi, Goro, Hirata, Koichi, Mizuguchi, Toru, Imai, Kohzoh, Takemasa, Ichiro, Sato, Noriyuki, Torigoe, Toshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676125/ https://www.ncbi.nlm.nih.gov/pubmed/31218770 http://dx.doi.org/10.1111/cas.14106

Ejemplares similares

Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series
por: Kubo, Terufumi, et al.
Publicado: (2019)

Ectopically Expressed Variant Form of Sperm Mitochondria-Associated Cysteine-Rich Protein Augments Tumorigenicity of the Stem Cell Population of Lung Adenocarcinoma Cells
por: Takahashi, Akari, et al.
Publicado: (2013)

Development of a T‐cell receptor multimer with high avidity for detecting a naturally presented tumor‐associated antigen on osteosarcoma cells
por: Watanabe, Kazue, et al.
Publicado: (2018)

Characterization of CD8(+) T-cell responses to non-anchor-type HLA class I neoantigens with single amino-acid substitutions
por: Shinkawa, Tomoyo, et al.
Publicado: (2021)

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480
por: Takaya, Akari, et al.
Publicado: (2016)

Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine
por: Shima, Hiroaki, et al.
Publicado: (2018)

Implication of chemo‐resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy
por: Shibayama, Yuji, et al.
Publicado: (2017)

ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway
por: Ogawa, Tadashi, et al.
Publicado: (2017)

ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD
por: Kawai, Noriko, et al.
Publicado: (2019)

GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis
por: Inoue, Ryuta, et al.
Publicado: (2017)

Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch repair–deficient colorectal cancer tissue
por: Hirama, Tomomi, et al.
Publicado: (2021)

Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy
por: Horibe, Ryota, et al.
Publicado: (2017)

Cellular stress induces cancer stem‐like cells through expression of DNAJB8 by activation of heat shock factor 1
por: Kusumoto, Hiroki, et al.
Publicado: (2018)

Osteosarcoma‐initiating cells show high aerobic glycolysis and attenuation of oxidative phosphorylation mediated by LIN28B
por: Mizushima, Emi, et al.
Publicado: (2019)

Fundamental and Essential Knowledge for Pathologists Engaged in the Research and Practice of Immune Checkpoint Inhibitor-Based Cancer Immunotherapy
por: Kubo, Terufumi, et al.
Publicado: (2021)

Development of an artificial antibody specific for HLA/peptide complex derived from cancer stem-like cell/cancer-initiating cell antigen DNAJB8
por: Tadano, Hiroki, et al.
Publicado: (2020)

Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP27
por: Yasuda, Kazuyo, et al.
Publicado: (2017)

Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells
por: Tanaka, Tsutomu, et al.
Publicado: (2015)

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer
por: Tanaka, Tsutomu, et al.
Publicado: (2017)

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level
por: Tanaka, Tsutomu, et al.
Publicado: (2016)

Immune responses to human cancer stem‐like cells/cancer‐initiating cells
por: Hirohashi, Yoshihiko, et al.
Publicado: (2015)

IL‐13 modulates ∆Np63 levels causing altered expression of barrier‐ and inflammation‐related molecules in human keratinocytes: A possible explanation for chronicity of atopic dermatitis
por: Kubo, Terufumi, et al.
Publicado: (2021)

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress
por: Saijo, Hiroshi, et al.
Publicado: (2016)

Spatiotemporal metabolic dynamics of the photosensitizer talaporfin sodium in carcinoma and sarcoma
por: Saito, Takuma, et al.
Publicado: (2020)

Palladium-Induced Temporal Internalization of MHC Class I Contributes to T Cell-Mediated Antigenicity
por: Ito, Koyu, et al.
Publicado: (2021)

Identification of a novel human memory T-cell population with the characteristics of stem-like chemo-resistance
por: Murata, Kenji, et al.
Publicado: (2016)

Non‐bacterial cystitis with increased expression of programmed death‐ligand 1 in the urothelium: An unusual immune‐related adverse event during treatment with pembrolizumab for lung adenocarcinoma
por: Ueki, Yohei, et al.
Publicado: (2020)

Cisplatin‐induced HSF1‐HSP90 axis enhances the expression of functional PD‐L1 in oral squamous cell carcinoma
por: Sasaya, Takashi, et al.
Publicado: (2022)

YTHDC2 Promotes Malignant Phenotypes of Breast Cancer Cells
por: Tanabe, Atsushi, et al.
Publicado: (2022)

Occult ovarian clear-cell carcinoma diagnosed as primary adenocarcinoma of the lung: A case report of a diagnostic pitfall for clinicians and pathologists
por: Kubo, Terufumi, et al.
Publicado: (2018)

Proteogenomic identification of an immunogenic antigen derived from human endogenous retrovirus in renal cell carcinoma
por: Kobayashi, Shin, et al.
Publicado: (2023)

Flap revascularization in patients following immediate reconstruction using an autologous free dermal fat graft for breast cancer: a report of two cases
por: Shima, Hiroaki, et al.
Publicado: (2016)

Identification of novel human leukocyte antigen‐A*11:01‐restricted cytotoxic T‐lymphocyte epitopes derived from osteosarcoma antigen papillomavirus binding factor
por: Li, Dongliang, et al.
Publicado: (2019)

Resovist-Enhanced MRI for Preoperative Assessment of Colorectal Hepatic Metastases: A Case of Multiple Bile Duct Hamartomas Associated with Colon Cancer
por: Suzuki, Hiroshi, et al.
Publicado: (2008)

Identification of characteristic subepithelial surface granulomatosis in immune‐related adverse event‐associated enterocolitis
por: Kubo, Terufumi, et al.
Publicado: (2021)

Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer
por: Tsuruma, Tetsuhiro, et al.
Publicado: (2008)

Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients
por: Kobayashi, Jun-ichi, et al.
Publicado: (2009)

Ileal strangulation by a secondary perineal hernia after laparoscopic abdominoperineal rectal resection: A case report
por: Tomohiro, Kurokawa, et al.
Publicado: (2017)

Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells
por: Morita, Rena, et al.
Publicado: (2014)

Primary Lung Adenocarcinoma With ALK Gene Rearrangement Mostly Occupied by the Signet-Ring Cell Carcinoma Component: A Case Report
por: Okimura, Akira, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_68t379al7a3d2e690d9hs13vik