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Mechanical loading mediates human nucleus pulposus cell viability and extracellular matrix metabolism by activating of NF-κB

Lower back pain is one of the most frequent complaints in US orthopedic outpatient departments. Intervertebral disc degeneration (IDD) is an important cause of lower back pain. Previous studies have found that mechanical loading was associated with IDD, but the underlying mechanism remains unclear....

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Xue, Chao, Lu, Ning, Ren, Peng, Peng, Haiwen, Wang, Yao, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676187/
https://www.ncbi.nlm.nih.gov/pubmed/31410113
http://dx.doi.org/10.3892/etm.2019.7744