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Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan

Introduction: The relationship between perinatal depressive symptoms, harm avoidance (HA), and a history of major depressive disorder (MDD) was examined in a prospective cohort study. Methods: This study was conducted from May 1, 2011, to December 31, 2016. A history of MDD was evaluated using the I...

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Autores principales: Kubota, Chika, Inada, Toshiya, Shiino, Tomoko, Ando, Masahiko, Aleksic, Branko, Yamauchi, Aya, Sato, Maya, Ohara, Masako, Murase, Satomi, Morikawa, Mako, Nakamura, Yukako, Okada, Takashi, Goto, Setsuko, Kanai, Atsuko, Ozaki, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676370/
https://www.ncbi.nlm.nih.gov/pubmed/31404277
http://dx.doi.org/10.3389/fpsyt.2019.00515
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author Kubota, Chika
Inada, Toshiya
Shiino, Tomoko
Ando, Masahiko
Aleksic, Branko
Yamauchi, Aya
Sato, Maya
Ohara, Masako
Murase, Satomi
Morikawa, Mako
Nakamura, Yukako
Okada, Takashi
Goto, Setsuko
Kanai, Atsuko
Ozaki, Norio
author_facet Kubota, Chika
Inada, Toshiya
Shiino, Tomoko
Ando, Masahiko
Aleksic, Branko
Yamauchi, Aya
Sato, Maya
Ohara, Masako
Murase, Satomi
Morikawa, Mako
Nakamura, Yukako
Okada, Takashi
Goto, Setsuko
Kanai, Atsuko
Ozaki, Norio
author_sort Kubota, Chika
collection PubMed
description Introduction: The relationship between perinatal depressive symptoms, harm avoidance (HA), and a history of major depressive disorder (MDD) was examined in a prospective cohort study. Methods: This study was conducted from May 1, 2011, to December 31, 2016. A history of MDD was evaluated using the Inventory to Diagnose Depression, Lifetime version during pregnancy. Depressive state and HA were evaluated during pregnancy and at 1 month postnatal using the Edinburgh Postnatal Depression Scale (EPDS) and Temperament and Character Inventory, respectively. The relationship between these variances was examined using structural equation modeling. Results: A total of 338 participants with complete data were included in the present study. Pregnant women with compared with those without a history of MDD were observed to have a significantly higher intensity of HA and more severe depressive symptoms in both the prenatal and postnatal periods. A history of MDD affected the severity of depressive symptoms [standardized path coefficient (SPC) = 0.25, p < 0.001] and the intensity of HA during pregnancy (SPC = 0.36, p < 0.001). The intensity of HA during pregnancy affected that at 1 month postnatal (SPC = 0.78, p < 0.001), while the severity of depressive symptoms as assessed by the EPDS during pregnancy affected that at 1 month postnatal (SPC = 0.41, p < 0.001). The SPC for perinatal HA to postnatal depressive symptoms (SPC = 0.13, p = 0.014) was significant and higher than that for perinatal depressive symptoms to postnatal HA (SPC = 0.06, p = 0.087). Conclusion: The present results suggest that early intervention in pregnant women with a history of MDD or a high intensity of HA is important to prevent postnatal depressive symptoms.
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spelling pubmed-66763702019-08-09 Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan Kubota, Chika Inada, Toshiya Shiino, Tomoko Ando, Masahiko Aleksic, Branko Yamauchi, Aya Sato, Maya Ohara, Masako Murase, Satomi Morikawa, Mako Nakamura, Yukako Okada, Takashi Goto, Setsuko Kanai, Atsuko Ozaki, Norio Front Psychiatry Psychiatry Introduction: The relationship between perinatal depressive symptoms, harm avoidance (HA), and a history of major depressive disorder (MDD) was examined in a prospective cohort study. Methods: This study was conducted from May 1, 2011, to December 31, 2016. A history of MDD was evaluated using the Inventory to Diagnose Depression, Lifetime version during pregnancy. Depressive state and HA were evaluated during pregnancy and at 1 month postnatal using the Edinburgh Postnatal Depression Scale (EPDS) and Temperament and Character Inventory, respectively. The relationship between these variances was examined using structural equation modeling. Results: A total of 338 participants with complete data were included in the present study. Pregnant women with compared with those without a history of MDD were observed to have a significantly higher intensity of HA and more severe depressive symptoms in both the prenatal and postnatal periods. A history of MDD affected the severity of depressive symptoms [standardized path coefficient (SPC) = 0.25, p < 0.001] and the intensity of HA during pregnancy (SPC = 0.36, p < 0.001). The intensity of HA during pregnancy affected that at 1 month postnatal (SPC = 0.78, p < 0.001), while the severity of depressive symptoms as assessed by the EPDS during pregnancy affected that at 1 month postnatal (SPC = 0.41, p < 0.001). The SPC for perinatal HA to postnatal depressive symptoms (SPC = 0.13, p = 0.014) was significant and higher than that for perinatal depressive symptoms to postnatal HA (SPC = 0.06, p = 0.087). Conclusion: The present results suggest that early intervention in pregnant women with a history of MDD or a high intensity of HA is important to prevent postnatal depressive symptoms. Frontiers Media S.A. 2019-07-26 /pmc/articles/PMC6676370/ /pubmed/31404277 http://dx.doi.org/10.3389/fpsyt.2019.00515 Text en Copyright © 2019 Kubota, Inada, Shiino, Ando, Aleksic, Yamauchi, Sato, Ohara, Murase, Morikawa, Nakamura, Okada, Goto, Kanai and Ozaki http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Kubota, Chika
Inada, Toshiya
Shiino, Tomoko
Ando, Masahiko
Aleksic, Branko
Yamauchi, Aya
Sato, Maya
Ohara, Masako
Murase, Satomi
Morikawa, Mako
Nakamura, Yukako
Okada, Takashi
Goto, Setsuko
Kanai, Atsuko
Ozaki, Norio
Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan
title Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan
title_full Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan
title_fullStr Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan
title_full_unstemmed Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan
title_short Relation Between Perinatal Depressive Symptoms, Harm Avoidance, and a History of Major Depressive Disorder: A Cohort Study of Pregnant Women in Japan
title_sort relation between perinatal depressive symptoms, harm avoidance, and a history of major depressive disorder: a cohort study of pregnant women in japan
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676370/
https://www.ncbi.nlm.nih.gov/pubmed/31404277
http://dx.doi.org/10.3389/fpsyt.2019.00515
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