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A statistical and biological response to an informatics appraisal of healthy aging gene signatures

Jacob and Speed did not identify even a single example of a ‘150-gene-set’ that was statistically significant at classifying Alzheimer’s disease (AD) samples, or age in independent studies. We attempt to clarify the various misunderstandings, below. ELECTRONIC SUPPLEMENTARY MATERIAL: The online vers...

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Detalles Bibliográficos
Autores principales:	Timmons, James A., Gallagher, Iain J., Sood, Sanjana, Phillips, Bethan, Crossland, Hannah, Howard, Robert, Kraus, William E., Atherton, Philip J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Correspondence
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676519/ https://www.ncbi.nlm.nih.gov/pubmed/31375147 http://dx.doi.org/10.1186/s13059-019-1734-z

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