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AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs)

BACKGROUND: The chemical carcinogen 3-methylcholanthrene (3MC) binds to the aryl hydrocarbon receptor (AHR) that regulates the expression of cytochrome P450 (CYP) enzymes as CYP1B1, which is involved in the oncogenic activation of environmental pollutants as well as in the estrogen biosynthesis and...

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Detalles Bibliográficos
Autores principales:	Cirillo, Francesca, Lappano, Rosamaria, Bruno, Leonardo, Rizzuti, Bruno, Grande, Fedora, Guzzi, Rita, Briguori, Sara, Miglietta, Anna Maria, Nakajima, Miki, Di Martino, Maria Teresa, Maggiolini, Marcello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676524/ https://www.ncbi.nlm.nih.gov/pubmed/31370872 http://dx.doi.org/10.1186/s13046-019-1337-2

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