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Comparison of outcomes between complete and incomplete congenital duodenal obstruction

BACKGROUND: Congenital duodenal obstruction (CDO) can be complete (CCDO) or incomplete (ICDO). To date there is no outcome analysis available that compares both subtypes. AIM: To quantify and compare the association between CCDO and ICDO with outcome parameters. METHODS: We retrospectively reviewed...

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Autores principales: Gfroerer, Stefan, Theilen, Till-Martin, Fiegel, Henning C, Esmaeili, Anoosh, Rolle, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676550/
https://www.ncbi.nlm.nih.gov/pubmed/31391773
http://dx.doi.org/10.3748/wjg.v25.i28.3787
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author Gfroerer, Stefan
Theilen, Till-Martin
Fiegel, Henning C
Esmaeili, Anoosh
Rolle, Udo
author_facet Gfroerer, Stefan
Theilen, Till-Martin
Fiegel, Henning C
Esmaeili, Anoosh
Rolle, Udo
author_sort Gfroerer, Stefan
collection PubMed
description BACKGROUND: Congenital duodenal obstruction (CDO) can be complete (CCDO) or incomplete (ICDO). To date there is no outcome analysis available that compares both subtypes. AIM: To quantify and compare the association between CCDO and ICDO with outcome parameters. METHODS: We retrospectively reviewed all patients who underwent operative repair of CCDO or ICDO in our tertiary care institution between January 2004 and January 2017. The demographics, clinical presentation, preoperative diagnostics and postoperative outcomes of 50 patients were compared between CCDO (n = 27; atresia type 1-3, annular pancreas) and ICDO (n = 23; annular pancreas, web, Ladd´s bands). RESULTS: In total, 50 patients who underwent CDO repair were enrolled and followed for a median of 5.2 and 3.9 years (CCDO and ICDO, resp.). CCDO was associated with a significantly higher prenatal ultrasonographic detection rate (88% versus 4%; CCDO vs ICDO, P < 0.01), lower gestational age at birth, lower age and weight at operation, higher rate of associated congenital heart disease (CHD), more extensive preoperative radiologic diagnostics, higher morbidity according to Clavien-Dindo classification and comprehensive complication index (all P ≤ 0.01). The subgroup analysis of patients without CHD and prematurity showed a longer time from operation to the initiation of enteral feeds in the CCDO group (P < 0.01). CONCLUSION: CCDO and ICDO differ with regard to prenatal detection rate, gestational age, age and weight at operation, rate of associated CHD, preoperative diagnostics and morbidity. The degree of CDO in mature patients without CHD influences the postoperative initiation of enteral feeding.
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spelling pubmed-66765502019-08-07 Comparison of outcomes between complete and incomplete congenital duodenal obstruction Gfroerer, Stefan Theilen, Till-Martin Fiegel, Henning C Esmaeili, Anoosh Rolle, Udo World J Gastroenterol Case Control Study BACKGROUND: Congenital duodenal obstruction (CDO) can be complete (CCDO) or incomplete (ICDO). To date there is no outcome analysis available that compares both subtypes. AIM: To quantify and compare the association between CCDO and ICDO with outcome parameters. METHODS: We retrospectively reviewed all patients who underwent operative repair of CCDO or ICDO in our tertiary care institution between January 2004 and January 2017. The demographics, clinical presentation, preoperative diagnostics and postoperative outcomes of 50 patients were compared between CCDO (n = 27; atresia type 1-3, annular pancreas) and ICDO (n = 23; annular pancreas, web, Ladd´s bands). RESULTS: In total, 50 patients who underwent CDO repair were enrolled and followed for a median of 5.2 and 3.9 years (CCDO and ICDO, resp.). CCDO was associated with a significantly higher prenatal ultrasonographic detection rate (88% versus 4%; CCDO vs ICDO, P < 0.01), lower gestational age at birth, lower age and weight at operation, higher rate of associated congenital heart disease (CHD), more extensive preoperative radiologic diagnostics, higher morbidity according to Clavien-Dindo classification and comprehensive complication index (all P ≤ 0.01). The subgroup analysis of patients without CHD and prematurity showed a longer time from operation to the initiation of enteral feeds in the CCDO group (P < 0.01). CONCLUSION: CCDO and ICDO differ with regard to prenatal detection rate, gestational age, age and weight at operation, rate of associated CHD, preoperative diagnostics and morbidity. The degree of CDO in mature patients without CHD influences the postoperative initiation of enteral feeding. Baishideng Publishing Group Inc 2019-07-28 2019-07-28 /pmc/articles/PMC6676550/ /pubmed/31391773 http://dx.doi.org/10.3748/wjg.v25.i28.3787 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Control Study
Gfroerer, Stefan
Theilen, Till-Martin
Fiegel, Henning C
Esmaeili, Anoosh
Rolle, Udo
Comparison of outcomes between complete and incomplete congenital duodenal obstruction
title Comparison of outcomes between complete and incomplete congenital duodenal obstruction
title_full Comparison of outcomes between complete and incomplete congenital duodenal obstruction
title_fullStr Comparison of outcomes between complete and incomplete congenital duodenal obstruction
title_full_unstemmed Comparison of outcomes between complete and incomplete congenital duodenal obstruction
title_short Comparison of outcomes between complete and incomplete congenital duodenal obstruction
title_sort comparison of outcomes between complete and incomplete congenital duodenal obstruction
topic Case Control Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676550/
https://www.ncbi.nlm.nih.gov/pubmed/31391773
http://dx.doi.org/10.3748/wjg.v25.i28.3787
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