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The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans
BACKGROUND: Central skull-base osteomyelitis (CSBO) represents a life-threatening complication of external ear canal infection. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in assessment of CSBO progression. METHODS: Twelve patients with CSBO were included in a retros...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676590/ https://www.ncbi.nlm.nih.gov/pubmed/31370785 http://dx.doi.org/10.1186/s12880-019-0331-7 |
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author | Mejzlik, J. Cerny, M. Zeinerova, L. Dedkova, J. Kopriva, J. Zadrobilek, K. Adamkov, J. Chrobok, V. Pellantova, V. |
author_facet | Mejzlik, J. Cerny, M. Zeinerova, L. Dedkova, J. Kopriva, J. Zadrobilek, K. Adamkov, J. Chrobok, V. Pellantova, V. |
author_sort | Mejzlik, J. |
collection | PubMed |
description | BACKGROUND: Central skull-base osteomyelitis (CSBO) represents a life-threatening complication of external ear canal infection. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in assessment of CSBO progression. METHODS: Twelve patients with CSBO were included in a retrospective clinical study. In total, 62 scans (30 CTs and 32 MRIs) were performed to evaluate the extent of inflammatory changes. The scans were read independently by two radiologists specialised in imaging of the head and neck. The regions under the skull base were specified using the online Anatomy Atlas of the skull base. To clarify the timeline, the time period was divided into four parts, and inflammatory changes in the skull-base regions were tracked. Data were statistically analysed. RESULTS: In early stages of the disease, CT scan detects inflammatory changes closely related to the stylomastoid foramen and medially to the posterior belly of the digastric muscle, changes which have been proved to be crucial for the diagnosis of CSBO. Later the infection spreads to the contralateral side causing demineralisation of the bones. CONCLUSION: Imaging methods play a crucial role not only in establishing the diagnosis, but also in anticipating the direction of infection spread underneath the skull base. |
format | Online Article Text |
id | pubmed-6676590 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-66765902019-08-06 The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans Mejzlik, J. Cerny, M. Zeinerova, L. Dedkova, J. Kopriva, J. Zadrobilek, K. Adamkov, J. Chrobok, V. Pellantova, V. BMC Med Imaging Research Article BACKGROUND: Central skull-base osteomyelitis (CSBO) represents a life-threatening complication of external ear canal infection. Computed tomography (CT) and magnetic resonance imaging (MRI) play key roles in assessment of CSBO progression. METHODS: Twelve patients with CSBO were included in a retrospective clinical study. In total, 62 scans (30 CTs and 32 MRIs) were performed to evaluate the extent of inflammatory changes. The scans were read independently by two radiologists specialised in imaging of the head and neck. The regions under the skull base were specified using the online Anatomy Atlas of the skull base. To clarify the timeline, the time period was divided into four parts, and inflammatory changes in the skull-base regions were tracked. Data were statistically analysed. RESULTS: In early stages of the disease, CT scan detects inflammatory changes closely related to the stylomastoid foramen and medially to the posterior belly of the digastric muscle, changes which have been proved to be crucial for the diagnosis of CSBO. Later the infection spreads to the contralateral side causing demineralisation of the bones. CONCLUSION: Imaging methods play a crucial role not only in establishing the diagnosis, but also in anticipating the direction of infection spread underneath the skull base. BioMed Central 2019-08-01 /pmc/articles/PMC6676590/ /pubmed/31370785 http://dx.doi.org/10.1186/s12880-019-0331-7 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Mejzlik, J. Cerny, M. Zeinerova, L. Dedkova, J. Kopriva, J. Zadrobilek, K. Adamkov, J. Chrobok, V. Pellantova, V. The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
title | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
title_full | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
title_fullStr | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
title_full_unstemmed | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
title_short | The routes of infection spread in central skull-base osteomyelitis and the diagnostic role of CT and MRI scans |
title_sort | routes of infection spread in central skull-base osteomyelitis and the diagnostic role of ct and mri scans |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676590/ https://www.ncbi.nlm.nih.gov/pubmed/31370785 http://dx.doi.org/10.1186/s12880-019-0331-7 |
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