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Sphere-forming culture enriches liver cancer stem cells and reveals Stearoyl-CoA desaturase 1 as a potential therapeutic target

BACKGROUNDS: The role of sphere-forming culture in enriching subpopulations with stem-cell properties in hepatocellular carcinoma (HCC) is unclear. The present study investigates its value in enriching cancer stem cells (CSCs) subpopulations and the mechanism by which HCC CSCs are maintained. METHOD...

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Detalles Bibliográficos
Autores principales:	Ma, Xiao-Lu, Sun, Yun-Fan, Wang, Bei-Li, Shen, Min-Na, Zhou, Yan, Chen, Jian-Wen, Hu, Bo, Gong, Zi-Jun, Zhang, Xin, Cao, Ya, Pan, Bai-shen, Zhou, Jian, Fan, Jia, Guo, Wei, Yang, Xin-Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676608/ https://www.ncbi.nlm.nih.gov/pubmed/31370822 http://dx.doi.org/10.1186/s12885-019-5963-z

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