Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation

We describe a method that adds long-read sequencing to a mix of technologies used to assemble a highly complex cattle rumen microbial community, and provide a comparison to short read-based methods. Long-read alignments and Hi-C linkage between contigs support the identification of 188 novel virus-h...

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Detalles Bibliográficos
Autores principales: Bickhart, Derek M., Watson, Mick, Koren, Sergey, Panke-Buisse, Kevin, Cersosimo, Laura M., Press, Maximilian O., Van Tassell, Curtis P., Van Kessel, Jo Ann S., Haley, Bradd J., Kim, Seon Woo, Heiner, Cheryl, Suen, Garret, Bakshy, Kiranmayee, Liachko, Ivan, Sullivan, Shawn T., Myer, Phillip R., Ghurye, Jay, Pop, Mihai, Weimer, Paul J., Phillippy, Adam M., Smith, Timothy P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676630/
https://www.ncbi.nlm.nih.gov/pubmed/31375138
http://dx.doi.org/10.1186/s13059-019-1760-x

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