Cargando…

Ursolic acid suppresses the invasive potential of colorectal cancer cells by regulating the TGF-β1/ZEB1/miR-200c signaling pathway

Ursolic acid (UA) is a biologically active compound, commonly used in traditional Chinese medicine (TCM). It has been reported to exhibit strong anticancer properties against a variety of cancers. Our previous studies showed that UA promoted apoptosis in colorectal cancer (CRC) cells and inhibited c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ling, Cai, Qiao-Yan, Liu, Jianxin, Peng, Jun, Chen, You-Qin, Sferra, Thomas J., Lin, Jiu-Mao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676672/ https://www.ncbi.nlm.nih.gov/pubmed/31452805 http://dx.doi.org/10.3892/ol.2019.10604

Ejemplares similares

miR-200b, ZEB2 and PTPN13 Are Downregulated in Colorectal Carcinoma with Serosal Invasion
por: Ranković, Branislava, et al.
Publicado: (2022)

miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1
por: Chu, Jessica Y.S., et al.
Publicado: (2019)

Expression of miR-9 and miR-200c, ZEB1, ZEB2 and E-cadherin in Non-Small Cell Lung Cancers in Iran
por: Nourmohammadi, Bahareh, et al.
Publicado: (2019)

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
por: Gregory, Philip A., et al.
Publicado: (2011)

WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells
por: Teng, Yong, et al.
Publicado: (2013)

Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion
por: Title, Alexandra C., et al.
Publicado: (2018)

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8(+) T cell fates
por: Guan, Tianxia, et al.
Publicado: (2018)

miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
por: GUO, FEI, et al.
Publicado: (2014)

Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-β1 in bladder cancer cells
por: Gao, Ruxu, et al.
Publicado: (2019)

Decitabine reverses TGF-β1-induced epithelial–mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis
por: Zhang, Nan, et al.
Publicado: (2017)

MiR-429 suppresses the progression and metastasis of osteosarcoma by targeting ZEB1
por: Deng, Yi, et al.
Publicado: (2017)

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
por: Burk, Ulrike, et al.
Publicado: (2008)

UTMD inhibit EMT of breast cancer through the ROS/miR-200c/ZEB1 axis
por: Shi, Dandan, et al.
Publicado: (2020)

The miR-200–Zeb1 axis regulates key aspects of β-cell function and survival in vivo
por: Title, Alexandra C., et al.
Publicado: (2021)

Decitabine reverses TGF-β1-induced epithelial–mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis [Corrigendum]
Publicado: (2017)

miR-340 and ZEB1 negative feedback loop regulates TGF-β- mediated breast cancer progression
por: Hou, Li-Kun, et al.
Publicado: (2016)

Inhibition of miR-141 and miR-200a Increase DLC-1 and ZEB2 Expression, Enhance Migration and Invasion in Metastatic Serous Ovarian Cancer
por: Wahab, Norhazlina Abdul, et al.
Publicado: (2020)

The ZEB1/miR-200c feedback loop regulates invasion via actin interacting proteins MYLK and TKS5
por: Sundararajan, Vignesh, et al.
Publicado: (2015)

circ-ZEB1 regulates epithelial-mesenchymal transition and chemotherapy resistance of colorectal cancer through acting on miR-200c-5p
por: Chen, Hongyu, et al.
Publicado: (2022)

miR-200c-141 Enhances Sheep Kidney Cell Reprogramming into Pluripotent Cells by Targeting ZEB1
por: Zhang, Yunfeng, et al.
Publicado: (2021)

Long noncoding RNA MAGI1-IT1 promoted invasion and metastasis of epithelial ovarian cancer via the miR-200a/ZEB axis
por: Gao, Hao, et al.
Publicado: (2019)

Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6
por: Gong, Yuhua, et al.
Publicado: (2018)

Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer
por: Sestito, Rosanna, et al.
Publicado: (2020)

Increased SIX‐1 expression promotes breast cancer metastasis by regulating lncATB‐miR‐200s‐ZEB1 axis
por: Zhu, Lizhe, et al.
Publicado: (2020)

YB1 regulates miR‐205/200b‐ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma
por: Liu, Xiumei, et al.
Publicado: (2021)

Long non-coding RNA ZEB1-AS1 predicts a poor prognosis and promotes cancer progression through the miR-200a/ZEB1 signaling pathway in intrahepatic cholangiocarcinoma
por: Jiao, Mingwen, et al.
Publicado: (2020)

MiR-200b attenuates IL-6 production through IKKβ and ZEB1 in human gingival fibroblasts
por: Matsui, Sari, et al.
Publicado: (2018)

MiR-200c-3p Modulates Cisplatin Resistance in Biliary Tract Cancer by ZEB1-Independent Mechanisms
por: Posch, Florian, et al.
Publicado: (2021)

TBX1 targets the miR-200–ZEB2 axis to induce epithelial differentiation and inhibit stem cell properties
por: Funato, Noriko, et al.
Publicado: (2022)

miR-655 Is an EMT-Suppressive MicroRNA Targeting ZEB1 and TGFBR2
por: Harazono, Yosuke, et al.
Publicado: (2013)

circKDM4C enhances bladder cancer invasion and metastasis through miR-200bc-3p/ZEB1 axis
por: Ma, Xueyou, et al.
Publicado: (2021)

MiR-4269 suppresses the tumorigenesis and development of pancreatic cancer by targeting ZEB1/OTX1 pathway
por: Sui, Xin, et al.
Publicado: (2020)

GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification
por: Chung, Vin Yee, et al.
Publicado: (2016)

Human trophoblast-derived exosomes attenuate doxorubicin-induced cardiac injury by regulating miR-200b and downstream Zeb1
por: Ni, Jie, et al.
Publicado: (2020)

LncRNA ZEB1-AS1 Regulates Colorectal Cancer Cells by MiR-205/YAP1 Axis
por: Jin, Zhong, et al.
Publicado: (2020)

miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells
por: NISHIJIMA, NOBUHIKO, et al.
Publicado: (2016)

miR-200 family controls late steps of postnatal forebrain neurogenesis via Zeb2 inhibition
por: Beclin, Christophe, et al.
Publicado: (2016)

A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration
por: Yang, Shanzheng, et al.
Publicado: (2018)

The miR-200c/141-ZEB2-TGFb axis is aberrant in human T-cell prolymphocytic leukemia
por: Erkeland, Stefan J., et al.
Publicado: (2021)

miR551b Regulates Colorectal Cancer Progression by Targeting the ZEB1 Signaling Axis
por: Kim, Kwang Seock, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vn3bb41mhenss03v4dvkfc5cun